Cholecalciferol (vitamin D3)
2400IU, 7200IU, 25 000IU, 50 000IU, and 100 000IU

• Cholecalciferol (Vitamin D3) is much more potent and has a longer duration of action the ergocalciferol (Vitamin D2).
• Cholecalciferol (Vitamin D3) is used to treat and prevent vitamin D deficiency and associated diseases, including rickets.
• Our cholecalciferol product comes in a 1 ml recyclable transparent PVC flapule® with dosage of 25.000IU, 50.000IU or 100.000IU. It can be used at a reduced frequency for treatment regimen : either weekly, bi-weekly or monthly according to therapy followed.

Publications :

• De Niet S, Coffiner M, Da Silva S, Jandrain B, Souberbielle JC, Cavalier E. A Randomized Study to Compare a Monthly to a Daily Administration of Vitamin D₃ Supplementation. Nutrients. 2018 May 23;10(6). pii: E659. doi: 10.3390/nu10060659.

• Cavalier E, Jandrain B, Coffiner M, Da Silva S, De Niet S, Vanderbist F, Souberbielle JC. A Randomised, Cross-Over Study to Estimate the Influence of Food on the 25-Hydroxyvitamin D₃ Serum Level after Vitamin D₃ Supplementation. Nutrients. 2016 May 20;8(5). pii: E309. doi: 10.3390/nu8050309.
• Bruyère O, Deroisy R, Dardenne N, Cavalier E, Coffiner M, Da Silva S, De Niet S, Reginster JY. A phase IV, two-armed, randomized, cross-over study comparing compliance with once-a-month administration of vitamin D3 to compliance with daily administration of a fixed-dose combination of vitamin D3 and calcium during two 6-month periods. Osteoporos Int. 2015 Dec;26(12):2863-8. doi: 10.1007/s00198-015-3205-z. Epub 2015 Jun 23.
• Schleck ML, Souberbielle JC, Jandrain B, Da Silva S, De Niet S, Vanderbist F, Scheen A, Cavalier E. A Randomized, Double-Blind, Parallel Study to Evaluate the Dose-Response of Three Different Vitamin D Treatment Schemes on the 25-Hydroxyvitamin D Serum Concentration in Patients with Vitamin D Deficiency. Nutrients. 2015 Jul 3;7(7):5413-22. doi: 10.3390/nu7075227.