NACYSTELYN
Mucolytic treatment with N-acetylcysteine L-lysinate Metered Dose Inhaler in Dogs: Airway Epithelial Function Change
R.P. Tomkiewicz, E.M. App, M. Coffiner, J. Fossion, P. Maes, M. King,
Eur. Resp. J., 1994, 7 : 81-87
Mucolytic synergism combining rhDNase and Nacystelyn in vitro in cystic fibrosis sputum
B. Dasgupta, M. King
Abstract, 1995 ERS Meeting, Barcelona, September 16 - 20, 1995,
Eur. Resp. J., 8 (Suppl. 19), 512s, 1995
A comparison of a new mucolytic N-acetylcysteine L-lysinate with N-acetylcysteine: airway epithelial function and mucus changes in dog.
R.P. Tomkiewicz, E.M. App, G.T. De Sanctis, M. Coffiner, P. Maes, B.K. Rubin, M. King,
Pulmonary Pharmacology, 1995; 8 : 259-265
Reduction in viscoelasticy of cystic fibrosis sputum in vitro with combined treatement by Nacystelyn and rhDNase
B. Dasgupta, M. King
Pediatr Pulmonology, 22 : 161-166 (1996)
Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in-vitro
A. Gillissen, M. Jaworska, M. Orth, M. Coffiner, P. Maes, E.M. App, A.M. Cantin, G. Schultze-Werninghaus
Resp. Med., 1997, 91 : 159-168
Effect of the mucoactive drug Nacystelyn on the respiratory burst of human blood polymorphonuclear neutrophils
A.M. Nagy, F. Vanderbist, N. Parij, P. Maes, P. Fondu, J. Neve
Pulmonary Pharmacology & Therapeutics, 1997, 10, 287-292
Optimization of a dry powder inhaler formulation of Nacystelyn a new mucoactive agent
Vanderbist, F., Wery, B., Moyano-Pavon, I., Moës, A.J.
J. Pharm. Pharmacol. 1999, 51 : 1229 – 1234
Deposition of Nacystelyn from a dry powder inhaler in healthy volunteers and cystic fibrosis patients
Vanderbist, F., Werry, B., Baran, D., Van Gansbeke, B., Schoutens, A., Moës, A.J.
Drug Dev. Ind. Pharm. 2001, 27 (3), 205-212
Nacystelyn inhibits oxidants-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells
Antonicelli F, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson K, MacNee W
Free Radic Biol Med 2002, Mar 15; 32(6) : 492-502
BUDESONIDE
Deposition and pharmacokinetics of budesonide from the Miat Monodose inhaler, a simple dry powder device
Ball DJ, Hirst PH, Newman SP, Sonet B, Streel B, Vanderbist F
International Journal of Pharmaceutics, Elsevier, 2002, vol. 245, pp 123-132
BUPRENORPHINE
Sensitive determination of buprenorphine and its N-dealkylated metabolite norbuprenorphine in human plasma by liquid chromatography coupled to tandem mass spectrometry.
Ceccato A, Klinkenberg R, Hubert Ph, Streel B
J Pharm Biomed Anal, 2003, Aug 8, 32 (4-5), pp 619-631
FENOFIBRATE
Randomised crossover studies of the bioequivalence of two fenofibrate formulations after administration of a single oral dose in healthy volunteers
Sonet B, Vanderbist F, Streel B, Houin G
Arzneim.-Forsch./Drug Res, 2002, vol.52, N°3, pp 200-204
LIDOSES
In vitro and in vivo behavior of some liquid or semi-solid filled hard gelatin capsules
Maes P, Brusselmans J, Sereno A, Pitti C, Sonck M, Coffiner M
Bulletin Technique Gattefossé, 1996, N°89, pp 63-70
PELLETS
Instrumentation of a gravity feed extruder and the influence of the composition of binary and ternary mixtures on the extrusion forces
Baert L, Fanara D, De Baets P, Remon JP
J Pharm Pharmacol, 1991, vol. 43, pp 745-749
Correlation of extrusion forces, raw materials and sphere characteristics
Baert L, Fanara D, Remon JP, Massart D
J Pharm Pharmacol, 1992, vol. 44, pp 676-678
PTH
Systemic delivery of parathyroid hormone (1-34) using inhalation dry powder in rats
Codrons V, Vanderbist F, Verbeeck RK, Arras m, Lison D, Préat V, Vanbever R
Journal of Pharmaceutical Sciences, May 2003, vol.92, N°5, pp 938-950
Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34)
from rat lungs
Codrons V, Vanderbist F, Ucakar B, Préat V, Vanbever R
Journal of Pharmaceutical Sciences, May 2004, vol.93, N°5, pp 1241-1252
TRAMADOL
Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol
Malonne H, Sonet B, Streel B, Lebrun S, De Niet S, Sereno A, Vanderbist F
Brit J Clin Pharmacol, 2003, vol. 57, N°3, pp 270-278
